| 대분류 | 소분류 | 요소기술 |
|---|---|---|
| Permeability | Permeability | Caco-2 cells permeability |
| MDCK cells permeability | ||
| PAMPA membrne Permeability | ||
| Plasma protein binding | Plasma protein binding | Plasma protein binding assay |
| Drug metabollism | Metabolic stabililty | Plasma stability |
| Microsomal stability | ||
| Hepatocyte stability | ||
| Metabolite profiling & ID | Metabolite profiling & ID | |
| Drug metabollism Reaction phenotyping | Reaction phenotyping for CYP (recombinant CYPs) | |
| Reaction phenotyping for UGT (recombinant UGTs) | ||
| Drug transporter | Drug transporter Reaction phenotyping | Reaction phenotyping for Transport |
| Reaction phenotyping for Transport (Kinetic study) | ||
| Drug-Drug interaction | Enzyme Inhibition | CYP Inhibition (Screening of CYP inhibition) |
| CYP inhibition (IC50 assay) | ||
| CYP inhibition (Ki assay) | ||
| UGT Inhibition (Screening of UGT inhibition) | ||
| UGT Inhibition (IC50 assay) | ||
| UGT inhibition (Ki assay) | ||
| Time-Dependent Inhibition (IC50 shift assay) | ||
| Time-Dependent Inhibition (Kinact/KI assay) | ||
| Microsomal binding assay | ||
| Transporter Inhibition | Transporter Inhibition (Screening) | |
| Transporter Inhibition (IC50 assay) | ||
| Transporter Inhibition (Ki assay) | ||
| Transporter inhibition (Time-Dependent Inhibition, IC50 shift assay) | ||
| Enzyme/Transporter Induction | Enzyme/Transporter Induction | |
| Enzyme Induction (EC50 assay) | ||
| PXR reporter assay | ||
| Cell viability | ||
| Bioanalytical services | Bioanalytical service | 약물분석법개발 |
| In vivo PK 혈장 분석 | ||
| Preclinical study | - | - |
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